This contribution presents psychiatric comorbidity rates, as found in the NEMESIS study. NEMESIS is a prospective population (18-64 years) study in the Netherlands with three measurements (1996, 1997, 1999). In the first measurement 7076 people have been interviewed. Of all people with a psychiatric DSM-III-R-disorder in the past twelve months, more than one third had at least two disorders. Women, low educated, unmarried and divorced people had a higher risk for comorbidity. The various mood disorders were mutually high comorbid like the anxiety disorders. Mood and anxiety disorders were also highly comorbid. Drugs dependence excepted, substance use disorders are not or low comorbid with other psychiatric disorders. Comorbidity was, in general, associated with a relatively high utilization of health care and use of medication. The results are in line with the international findings.